Protein C, Total Antigen
Ordering Recommendation
Not recommended for detecting protein C deficiency; preferred test is Protein C, Functional (0030113). Use to subtype deficiency in known protein C-deficient individuals. Do not order if individual has been on warfarin therapy in the previous 2-4 weeks.
New York DOH Approval Status
Specimen Required
Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.
Transfer 2 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Serum. EDTA plasma, clotted or hemolyzed specimens.
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months, at -70°C: 6 months
Methodology
Enzyme Immunoassay
Performed
Sun-Sat
Reported
1-2 days
Reference Interval
1-4 days: 17-53%
5-29 days: 20-64%
30-89 days: 21-65%
90-179 days: 28-80%
180-364 days: 37-81%
1-5 years: 40-92%
6-10 years: 45-93%
11 years and older: 63-153%
Interpretive Data
Patients on warfarin may have decreased protein C values. Patients should be off warfarin therapy for two weeks for accurate measurement of protein C.
FDA
Note
Hotline History
CPT Codes
85302
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0030111 | Protein C, Total Antigen | 27820-0 |
Aliases
- Protein C Antigen, Plasma
- Protein C Immunologic